Divi Venkateswarlu

Research Interests

Protein structure, function and dynamics Structural Basis of Blood coagulation Protein-Protein interactions in blood clotting cascade

Recent Publications

• Lidija Kovacic, Adrijana Leonardi, Cho Koh, Jernej Sribar, Alenka Bakija, Manjunatha Kini, Divi Venkateswarlu, Igor Krizaj, Zorica Latinovic (2018). (The First Intrinsic Tenase Complex Inhibitor with Serine Protease Structure Offers a New Perspective in Anticoagulant Therapy). In David Gailani, (10) 118, pp. xxxx-xxxx. Thrombosis and Hemostasis.
• Divi Venkateswarlu (2014). (Role of hydrophobic mutations on the binding affinity and stability of blood coagulation factor VIIIa: a computational molecular dynamics and free-energy analysis.). (1) 450, pp. 735-40. Biochemical and biophysical research communications.
• Divi Venkateswarlu (2010). (Structural investigation of zymogenic and activated forms of human blood coagulation factor VIII: a computational molecular dynamics study). In Simon Harold, (7) 10, pp. 20 . BMC Sructural Biology.
• C Colina, Divi Venkateswarlu, R Duke, L Perera, L Pedersen (2006). (What causes the enhancement of activity of factor VIIa by tissue factor?). (12) 4, pp. 2726-9. Journal of thrombosis and haemostasis : JTH.
• Lalith Perera, Thomas Darden, Robert Duke, Divi Venkateswarlu, Lee Pedersen (2004). (Early Unfolding Response of a Stable Protein Domain to Environmental Changes). Journal of Physical Chemistry.
• Divi Venkateswarlu, R Duke, L Perera, T Darden, L Pedersen (2003). (An all-atom solution-equilibrated model for human extrinsic blood coagulation complex (sTF-VIIa-Xa): a protein-protein docking and molecular dynamics refinement study.). (12) 1, pp. 2577-88. Journal of thrombosis and haemostasis : JTH.
• Divi Venkateswarlu, L Perera, T Darden, L Pedersen (2002). (Structure and dynamics of zymogen human blood coagulation factor X.). (3) 82, pp. 1190-206. Biophysical journal.
• Divi Venkateswarlu, S Krishnaswamy, T Darden, L Pedersen (2002). (Three-dimensional solution structure of Tropidechis carinatus venom extract trocarin: a structural homologue of Xa and prothrombin activator.). (10) 8, pp. 302-13. Journal of molecular modeling.
• Divi Venkateswarlu, David Ferguson (1999). (Effects of C2-Substitution on Arabinonucleic Acid Structure and Conformation). 121, pp. 5609-5610. Journal of American Chemical Society.
• Divi Venkateswarlu, Jerzy Leszczynski (1999). (Py*Pu*Py Type Triplexes with Modified Bases: Ab Initio SCF-MO Studies toward Improved DNA Recognition). 103, pp. 3489-3494. Journal of Physical Chemistry A.
• Divi Venkateswarlu, K Lind, V Mohan, M Manoharan, Daniel Ferguson (1999). (Structural properties of DNA:RNA duplexes containing 2'-O-methyl and 2'-S-methyl substitutions: a molecular dynamics investigation.). (10) 27, pp. 2189-95. Nucleic acids research.
• Yuri Rubin, Yuri Morozov, Divi Venkateswarlu, Jerzy Leszczynski (1998). (Prototropic Equilibria in 4-Thiouracil: A Combined Spectroscopic and ab Initio SCF-MO Investigation). 102, pp. 2194-2200. Journal of Physical Chemistry A.
• Divi Venkateswarlu, J Leszczynski (1998). (Tautomeric equilibria in 8-oxopurines: implications for mutagenicity.). (4) 12, pp. 373-82. Journal of computer-aided molecular design.
• Divi Venkateswarlu, Jerzy Leszczynski (1998). (Tautomerism and Proton Transfer in 6-Selenoguanine: A Post Hartree-Fock Level ab Initio SCF-MO Investigation). 102, pp. 6161-6166. Journal of Physical Chemistry A.
• Divi Venkateswarlu, Richard Lyngdoh (1997). (Deglycosylation of alkylated nucleosides: a molecular orbital study). 418, pp. 49-57. Journal of Molecular Structure (Theochem).
• Divi Venkateswarlu, Richard Lyngdoh (1997). (Mutagenic significance of proton acidities in methylated guanine and thymine bases and deoxynyucleosides:A thoretical study). 393, pp. 151-161. Journal of Molecular Structure: THEOCHEM.
• Divi Venkateswarlu, Richard Lyngdoh (1995). (Proton-transfer reactions of nucleic acid bases: A semiempirical molecular orbital study). (3) 107, pp. 221-231. Proceedings of the Indian academy of Sciences-Chemical Sciences.
• Divi Venkateswarlu, Richard Lyngdoh (1995). ( STRUCTURAL, STERIC AND ENERGETIC REQUIREMENTS FOR INDUCTION OF BASE SUBSTITUTIONAL MUTATIONS BY METHYLATED GUANINES AND THYMINES). (4) pp. 839-846. Journal of Chem. Soc. Perkin Trans.2.